The article doesn't talk about all the costs of dealing with regulations, licenses, and all the other red tape to get a drug approved in the US. I'm not defending the drug companies, but if they didn't have to spend years on that stuff it would cut costs. Then there are the required clinical trials...successful trials cost money, and failed trials cost even more. The company doesn't make any money until after all that. And what about patents? That adds even more to the cost. Plus, big pharma gives 'discounts' to other countries to prevent them from copying the drug. So, we end up paying extra to make up the difference.