Why isn't Lilly hyping Reta?

I agree with Jamie09. They're making a killing on tirzepatide and don't want to cut into their profits until they're fully ready to launch retatrutide. And that CEO really needs to get the pronunciation right (Reht a TRU' Tied, as suggested by PurePal).
 
When I first saw the name, I mispronounced it like the CEO in the video that Compound_Goals linked. But then I think I saw a video of him pronouncing it like I typed in my earlier comment. Anyway, they'll probably come up with even worse brand names.
 
Exactly this.

In my opinion, they are going to intentionally delay retatrutide's market release to squeeze every last penny out of tirzepatide. As soon as retatrutide gets FDA approval and hits the market, everyone will want the newest, shiniest thing, and demand for name-brand tirzepatide will plummet.
 
I'm curious about their timing. Even with tirzepatide's release, Ozempic sales still grew by about 25% in 2024 and are up another 15% YOY through Q2 2025. Novo claims the growth is slowing, but 15% is still impressive.

If tirzepatide's growth mirrors or exceeds semaglutide's, I wonder if they'll delay retatrutide even past approval to maximize profits, or if they even can.
 
I think a lot depends on how patent law plays out. Maximizing the exclusivity window is crucial, so I'm sure they have teams of analysts crunching numbers to determine the optimal timing for every action.

Novo's progression from liraglutide to semaglutide and Lilly's dulaglutide to tirzepatide may offer some clues about future GLP releases. It'll be interesting to see how it all unfolds.
 
I worry about waiting too long to release retatrutide, considering the rapid development of potentially more effective drugs. Bioglutide, for example, is a quadruple-receptor agonist in Phase 2 trials as both an oral and combined formulation.

https://firstwordpharma.com/story/5...tigational, oral,many of which are injectable

Bioglutide supposedly works better, faster, with fewer side effects, and minimizes bone/muscle loss. And, of course, it instantly enhances... well, never mind. 😉
 
If they suspected significant liver damage, they would halt the trials immediately. Lilly wouldn't take that risk, and the TRIUMPH and other Phase 3 trials have independent data monitoring committees that would pull the plug if safety concerns arose.
 
I'm always fascinated by the decision-making processes within big pharma. It's probably a chaotic mess of 'experts' trying to outsmart each other, with major decisions ultimately decided by a coin flip, lol.
 
Guys, I'm a young dude, 21, and a bit overweight (6' 2" and 265 lbs). I've been on Reta for a couple of weeks. The first week, at 500mcg every 3 days, was amazing. Now, I'm at 1mg weekly and not feeling it as much. My appetite is back. I eat mostly fats and protein, avoiding carbs.
 
Jamie09 said:
Guys, I'm a young dude, 21, and a bit overweight (6' 2" and 265 lbs). I've been on Reta for a couple of weeks. The first week, at 500mcg every 3 days, was amazing. Now, I'm at 1mg weekly and not feeling it as much. My appetite is back. I eat mostly fats and protein, avoiding carbs.
Click to expand...

0.5mcg every 3 days is less than 1mg a week. Inject at least twice a week and increase the dose until you feel the appetite suppression again. Could also be a bunk product or underdosed. The therapeutic dose is 2-12mg weekly!
 
You seem like a decent guy, Jamie09, but honestly, at 21, have you tried lifestyle changes before messing with your body? The body can heal itself if you give it the right direction.
 
I was worried after having some bad side effects with sema and tirz, but I gotta say, Reta seems pretty good so far. Minimal side effects, but I'm definitely seeing fat loss! I started at 1mg a week and now I'm at 4mg. Dropped about 20 pounds in two months and I'm back in my old jeans. I'm active, so my routine hasn't changed, and I try to eat well.
 
My girlfriend and I are both using Reta now! We're not overweight, but it helps suppress cravings and gives a little metabolic boost. I'm using 2.5mg weekly. No real heart rate changes, but there's a slight loss of libido, probably from reduced dopamine.
 
Wait, Molly from JEEP isn't an actual person sending you face-blowing-a-kiss pictures? Turns out Molly is probably more of a Mike? Honestly, still less fake than what Eli Lilly is doing.
 
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