Reta - Anyone Feeling It?

Pip Great to hear as someone newer to Reta. Are your doses split? I would love to tone down cravings without killing appetite completely. Thanks!

4mg is out of the question for me, 1 is plenty. Around week 6-7 currently, some hunger is coming back. My plate is mostly protein, roughly 75%, plus good carbs. The scale keeps dropping while my muscle holds steady. Honestly, big fan. Reta has completely shifted how I think about food and drinks.

Three weeks is early, so give it time and follow the recommended escalation schedule, you haven't reached a therapeutic dose yet. The trials show some low responders, but they're clearly a minority, and retatrutide looks like the strongest obesity drug so far for most people. I also think the trial numbers undersell what happens at the higher doses. Several participants have said online that once they hit their goal weight they quietly skipped doses and stashed pens instead of quitting or telling the provider. Not ethical, but understandable when you'd be cut off after the study and could regain. Compliance would probably be better if every participant were promised some follow-up maintenance treatment after the trial ends.

Appetite goes through phases for everyone, totally normal even on the med. No need to raise the dose right away, and I think following the manufacturer's guidance alongside your doctor matters, since the official instructions were at least properly tested, unlike other doses and methods. Honestly 5 mg is treating me well so far: I get to ponder what I fancy, eat a decent amount and live a fairly normal life. On 2.5 mg my appetite was basically dead, all food looked gross and I forced myself to eat, especially out. I want my appetite regulated but still enjoy a meal, even a few bites. I worried about health problems from so few nutrients, so I focused on protein, which I still do.

Eight weeks into reta after switching off MJ. Appetite control was pretty weak the first four weeks, started picking up once the dose went higher. Felt a little unsure about the switch at first, but my doctor had me stick it out for eight weeks given my cholesterol numbers and a couple other things. Starting to see real change now, appetite quiets down each time the dose bumps, and the fat around my stomach specifically seems to be shifting. Barely any stomach issues either. Not in the US, so all of this is happening under a doctor's supervision, just noting that. Curious to see where this goes, especially after two years on MJ maintenance before this switch.

Up until a couple weeks ago I'd have said no to that - I've been strict about it, tracking everything, eating protein until I can't anymore, forcing myself through workouts even when I didn't want to. All hard work, just with some help from the medication. But somewhere around two months into 10mg, something flipped. It's actually easy now. Hunger just isn't there anymore, and I have to consciously make myself eat enough, which is wild given how much my whole life used to revolve around food. Couldn't agree more with whoever said that. This dose is clearly the right fit for me, and even though I know I can't stay on it forever, I'm enjoying every bit of not thinking about food right now.