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The marker improvement at 100 lbs is the story underneath the weight number - a1c coming down from 5.7 is early enough to stop the trajectory before it becomes a problem. 100 lbs changes the whole metabolic picture.

Weekly is simpler to track and easier to manage socially - split dosing is mostly for GI management. If once weekly is working, stay there.

Hold under tongue 60-90 seconds before swallowing. Works best for GI use cases.

Been on Mounjaro 2.5 years, always paid $25/month or $75 for 3 months. April 1 it jumped to $489/month. I'm T2D, A1c sits at 5.3–5.5, got good coverage. BCBS says my coupon expired. Pharmacy's seeing this a lot, thinks insurance moved Mounjaro from tier 1 to tier 3. Can't afford the drug and pay...

Wasn't asking the forum to manage my treatment — the docs already covered the medical side. What I wanted was real user experience from folks who've been through it. Doctors are great but they don't have your day-to-day perspective.

Started on Mounjaro in August for diabetes and weight. Hit 5mg and stayed there, dropped 62 pounds and reached goal weight. A1c is now 5.2. Wild thing—that big vein I had on my inner thigh forever? It's just gone now.

between one and two pm i just crash and need to sleep. eating 100g protein, could drink more water, more active than usual. wasn't an issue with the oral version, just the shots. not sure what to do about naps with two kids.

Gray market's the way. Google it — you can find compounded versions online. Affordable, mix it yourself (easy), no insurance drama, any dose you want.

I'm exactly the same - three years, 20 percent down, same height and weight. I'm older and diabetic too. work out four days a week but diet could be better. sleep's usually solid. sometimes I think I hit a set point I was at for years. studies say 20 percent for a reason.

Could be seasonal too—'before' was heading into winter, 'after' is post-winter. You look less tan in the second shot which hits different. Confidence does that. Might dig deeper in therapy about how much appearance ties to how you feel.

Some folks get constipation, some get the opposite. If you lean one way and get the opposite, there you go. I tended toward constipation after boosting protein after years of IBS stuff. Swung to the other side but tirz leveled it out. I'm the most regular I've been in a long time. Heard this...

I saw someone mention something about "man boobs" from these meds. Is that even a thing? I'm a little worried now.

The best advice I got was from my sister. She said don't overbuy groceries thinking you'll want to eat specific items. She was spot on. My cravings change every week. I shop weekly and keep my pantry pretty bare. Keep feeding your family as usual, but hold off on buying special stuff for...

gained weight fast from antipsychotics, was at 155. now at 123, back where i was before meds. been maintaining for about a year and a half and feel so much happier in my body. worked really well for me.

WHY DID I NOT THINK OF THIS?!?! You're a GENIUS!

I totally understand Owl_Grind! I felt so much better when I was on it before. Fingers crossed it works the same way this time around!

Thanks Chris_16, that's really helpful! I was wondering about the dosage. I think I will try that.

I don't get it. My pens have the dose marked with numbers right on them...

Has anyone been on a GLP-1 like Ozempic, stopped, and then started again later? I was on Ozempic for about half a year 3 years ago, and gained back around 50 pounds. I've been back on for 3 weeks now, still at the starting dose of 0.25mg. So far, no side effects. Just curious about others'...

I agree with keeping old clothes! I had a pair of jeans that were a UK size 20 (US 16 maybe?) that were super tight. Now those jeans just fall right off me!