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Non-diabetic use accounts for the majority of semaglutide prescriptions now - the STEP trials on weight specifically included both T2D and non-T2D populations. The weight loss outcomes for non-diabetics tend to be larger in absolute terms because the baseline A1c-correction effect doesn't...

Source Discussion unlocks once you have some participation history - a few genuine replies on GLP-1 topics gets you there fast. Prostamax peptide threads have decent coverage once you can access that section.

The markup frustration is real - paying this much out of pocket and then reading a blindness lawsuit headline is a different experience than it would be for a cheap generic.

Just NMN and creatine. Protein powder too if that counts.

Update: down 4 lbs since a few days ago. Body wanted to recalibrate first. All this talk about orange cap batches is making me wonder if mine was from that run. Got mid-Feb from a reseller, had the orange cap, nasty runs and burps. Switched to a different T60 vial and zero side effects now.

Sorry you're dealing with this. I don't have medical advice but ME/CFS forums might help—a friend's mom found real answers and functional life again after symptoms. Not 100% back but loads better than before.

prednisone messed me up with steroid-induced diabetes. went into keto acidosis, losing a pound a day for 2 months straight. constant nausea, lightheaded, brutal triglycerides. my doc said i couldn't do anything about it. that's when i started running and haven't stopped in 3+ years. proved him...

0.25mg for two months was perfect — no side effects, zero food noise, no cravings, no punishment meals. Then bumped to 0.5mg. Week one fine. Week two rough. Got stressed, started emotional eating big portions. Now big meals = diarrhea, burping, gas, stomach pain nonstop for a week. Exhausted and...

Just curious, anyone else deal with hypothyroidism or other conditions while on these meds? Kinda wondering how that all interacts with exercise.

Thanks for the suggestions everyone. I might look into reformer Pilates, RamblinMan1972, that sounds less intimidating than a regular gym. And I like the idea of fitness games, Mel, I do have a Switch...

I've been using this stuff since late 2025. I'm down close to 35 pounds, which is awesome. I feel great and seeing myself in pictures is a real motivator. I've been trying to eat better, doing more cooking, experimenting with recipes I wouldn't have touched before. I'm even reading nutrition...

What's a TDEE calculator?

Seriously needed to read this. Thanks!

Thanks, MrsFit. I'm definitely going to reach out. Smaller meals are a good call, I'll try that.

Thanks for the support, everyone! Morgan07, I needed to read this today. I’m just wrapping up week 2 and I feel terrible. Seriously considering quitting.

Get therapy. Seriously. That's a flat stomach. Easily in the top 5% of women.

Hey everyone, this is for those in the thick of the early struggles with these meds. I posted maybe a year back, ready to throw in the towel because of the awful stomach issues, feeling sick, the sulfur burps, and just being wiped out. Everyone's gotta figure out if the downsides are worth it...

First of all, congrats!!! You inspire me so much to continue my journey and stay positive to overcome obstacles. Can I ask, what do you do to have great skin? I'm worried about sagging after losing weight. Can you give me advice??

Sadly, a tummy tuck is probably the only thing that's really going to make a significant difference (skin removal). I'm saying this from personal experience. I've been trying creams, muscle building, light therapy, and even those radio frequency treatments for YEARS. Nothing has worked. I talked...

I'm super impressed by your results! I hope you're proud of how far you've come. You're a completely different person!