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My dad's been trying to lose weight, docs prescribed him semaglutide. Month and a half in at 1mg and he says it makes him feel gross every time I see him. Should he drop dose? Stop and restart? I don't know enough to help—looking for advice here.

I just meant that 1 in 10 from a study is not the same as 1 in 10 overall. I'm a subscriber to that paper, and their reporting is usually good. I think people need to be critical thinkers.

The article opens with someone on another GLP for over a year and maybe lost a pound. I've been a low-responder myself. I got sick when I jumped to 5mg a week. I had to lower the dose to prevent the effect, splitting 2mg into separate injections each week. I slowly went up again at 0.5 mg every...

I have to push through eating boiled eggs plus protein bars. Up at 3:30am and food doesn't enter my thoughts till afternoon around 2pm or later.

Just love bidets honestly. Spouse added one to the toilet and I can say it's completely changed everything for me.

Actually, what the article *really* says is that one in ten people in a clinical trial were considered "non-responders". That does NOT mean they had zero response, just a smaller one. It's not the same as saying 1 in 10 *overall*. This is the kind of thing that makes science reporting suspect...

Solid graphing work totally my bad with the stereotype wasn't expecting that after all the data.

Blood sugar has dropped as low as 9 mg/dL (with outside insulin, crazy scenario) with no bad effects (heavy ketone load). Not for everyone, but there are studies on extreme fasting and weird diets we can't run anymore. Link above if you like the hardcore stuff.

I just started a couple of weeks ago. I'm going into week 7, and I'm hoping I'll finally start seeing a big difference. I'm not happy about the cold and insomnia, especially since I'm not seeing much weight loss. Does it get better?

I've noticed that even though I'm eating less, I'm wasting tons of food now! Like, I'll get takeout and only eat half. Anyone else have that issue?

Definitely bring up slowing down with your doc. I decided to stop at the 1mg dose, and it's been doing the trick for me.

Before I even lost weight, my snoring stopped.

It's inspiring to see the real changes you've made using Mounjaro.

I hung back on the starting dose for ages 'cause it was working and I didn't want to max out too soon. Patience is key!

I actually quit smoking!

huge change. congrats. side-by-side pics are so helpful to see the differences over time.

Raising your dose when side effects already bother you on half-why? Doesn't track logically.

I'd be worried about slowing down horse digestion. All us horse people know how their stomachs are and colic is super dangerous. Maybe look into BPC157/TB500 and KPV for fixing gut issues and reducing swelling. I just put one of my horses on it, so I don't know if it works yet, but he's doing...

That's a good point, but this is interesting to think about. People always pass off human obesity by blaming it on people not moving enough or being bad at calories. It's harder to say that housecats have gotten less active lately, maybe the ingredients of cat food have changed?

That's awesome! How are you feeling about the change?