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To answer Rory_2004, the patent expiration simply allows generic manufacturers to produce the drug. It will still take time for them to get approval and manufacture it. Expect generics maybe by next year. Some are estimating they might be 60-70% cheaper when they finally hit stores.

I still drink occasionally. The difference is now I might have one or two drinks twice a week, whereas before it was closer to six or eight every day LOL

been on selank subcutaneous for two weeks and... nothing. just nothing after two weeks at a solid dose. gonna try nasal spray next. also on modafinil through my doc and that works great - just need the right dose. more than one pill a day and i crash hard.

Started this a year ago. Lost about 50 lbs in 5 months, then plateau for 5 months. Then it woke me up 10 times a night. Switched to Mounjaro, lost 4 more lbs, plateau again. I'm at 135kg, started at 163kg. Paying 400 euros a month for nothing. Can't afford the 12.5 dose. Any tips?

Fantastic progress Kelly_1976! Keep up the great work!

Eye issues might be from Mounjaro, but research leans more toward semaglutide alone (Ozempic/Wegovy) for this kind of nerve problem. Tirzepatide seems to stabilize the eye effects compared to sema by itself. Also closely tied to high blood pressure and sharp A1c drops. Monitor those numbers hard...

Try zinc a few days before and after Botox—supposedly makes it last longer. Even regular exercise and sauna kill my Botox way faster than sitting around.

tons of things could be playing a role in gaining. are you in a deficit? did you recalculate your tdee? what dose and is it time to go up? exercise and strength training? enough protein and fiber? bloodwork show any nutrient gaps? tracking blood sugar? talked to your doc?

0.5 was the dose where I finally had dependable appetite suppression. I was told that the lower doses are mainly for adjustment initially.

I remained there until the weight loss stopped, which was about half a year. Lost nearly 70 pounds, then went up to the next dose. I'm maintaining now at 1.7, and have been for two years. Lost 140 pounds total.

T2D here, been on 2mg about 9-10 months, plateau hit 2 months ago. Doctor gave me the option to switch brands if this stops working. Don't see them until July so we'll see. My mom's also T2D, was on the first one for years at 2mg, switched because her new doctor pushes the second one. She's lost...

The towel wrapping is the kind of non-scale victory that the number on the scale could never capture - these are the markers that make the trajectory feel real in a way the morning weigh-in doesn't.

Appreciate it. This year is finally about me getting healthier. I'm lifting six days a week, running on weekends, and honestly just feel more like myself than I have in years.

Damn I was too late getting those filters - they were like a dollar a piece from china with free shipping. Would definitely look into them if there's stock.

Are you tracking your calories or anything like that?

It is interesting to note that a small percentage of patients on GLP-1 receptor agonists may experience new-onset erectile dysfunction, particularly those with pre-existing hypertension or who experience less significant weight loss.

Concerning pre-reconstituted peptides, I'd advise caution. I saw a discussion where someone received ipamorelin/cjc-1295 already mixed. It's best to inquire about shipping conditions, specifically if it was shipped cold. The stability of peptides in solution is significantly affected by...

For those considering semaglutide and who have a history of acid reflux, it's wise to consult with your doctor first. GLP-1s can sometimes worsen acid reflux. Starting with a very low dose and slowly increasing it might be helpful.

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I can't stand chicken thighs anymore. Used to be my go-to.