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Yep, definitely lost noticeable strength and stamina during my time on Ozempic. My top piece of advice is to lean hard into protein intake and keep strength training as consistently as you can manage.

Down 40 percent from my starting weight. At goal now. Lost around half a pound weekly. Took a full year. Still losing, just very slowly. On it for type 2. Great that you're walking and lifting, really helps build muscle.

If the side effects get to be too much, you can always drop the dose a bit, nothing to be scared of there. Honestly this has been the easiest weight loss method I've ever come across. Even quieted down my urge to drink.

Fantastic!! Congrats on all that hard work paying off! Your progress is genuinely inspiring, still dealing with a hanging belly myself and it honestly feels like it's never going anywhere.

That's genuinely amazing, congrats!! Totally relate to that shoe-tying breath-holding thing. Keep it going, fit's clearly right around the corner. Honestly the thing that worries me a bit is losing weight too quickly and ending up with loose skin.

Yep, quit drinking before starting sema, had exactly one vodka mixed into a big glass of fizzy water and it left me unbelievably nauseous. Safe to say cutting alcohol entirely is the way to go.

I get it, that's rough. Started at 263 myself and didn't see or feel anything working until I hit 7.5mg. Patience, it'll click eventually, trust the process. My rule was a month, two max, and if nothing changed by then I'd bump the dose. Sitting at a low amount long-term works great for some...

Man, this is genuinely helpful, wouldn't have thought to keep a journal without seeing this. Really appreciate it. And huge congrats on the incredible milestone!

Ha, funny how quickly I ended up with over four thousand milligrams of tirz and about fourteen hundred of reta, and haven't even touched the reta yet, probably a few months out still.

Yes! That's exactly how I felt yesterday honestly. Kept wondering what went wrong since I'd never felt that rough before. Going to look ahead at my schedule though and see if shifting shot day makes sense around upcoming plans.

Roughly six weeks in now and things are starting to improve. Takes a while to get through if side effects show up, but was advised to push through it.

Same pen as you here, over in the UK. Have to screw a fresh needle on each time. I'm at 7.5mg now and only really started dropping weight once my dose climbed. Don't lose hope yet.

the intentional no-grazing structure is the part that maintains the deficit without counting calories - if the only food going in is at deliberate meals and snacks rather than ambient picking, the medication's appetite suppression can do its job between those windows. protein at every eating...

Non-responders at the lower doses are definitely a thing. A lot of people don't feel anything until 7.5 or 10mg. Getting to 10mg through insurance sounds like good timing. Are you feeling any appetite changes at all, or has it been basically nothing so far??

The 1.4mg pen-click option sitting between 1.0 and 2.0 is worth knowing about if the dose needs adjusting before committing to the full step up. 8 lbs in the first week at 0.25 is a strong early signal - some people maintain that pace through the lower doses before needing to increase. What does...

Getting prescribed when you have clear clinical indicators like PCOS and the doctors are still pushing back is incredibly frustrating. What did the conversation with your doctor look like and what finally got them to agree to prescribe? The OP's PCOS result is exactly the use case the medication...

The muscle loss profile on Reta tracks with deficit rate, not medication-specific mechanism - the glucagon component doesn't add the protective effect that was initially claimed. Starting at 270 and down 74 lbs, the composition outcome at this pace follows resistance training frequency and...

The mirror always lags behind the pants - self-perception updates last.

Patent expiry makes generics viable within 1-2 years - sema's patents roll off 2026-2027.

Woah, is that really you? You look like you've turned back the clock!