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First week side effects are often the worst it gets - the body adjusts over the following weeks and most people find week three or four looks very different. Hanging in is the right call at this stage.

Compounding cuts the cost significantly - that's the most practical near-term answer.

Face changes are one of the more striking markers because the face holds fat in ways the rest of the body doesn't show in photos - people who know you notice it first. The Reddit exercise-banning pattern is a moderation overcorrection, and most GLP-1 forums are more open to the metabolic...

To @LiquidGold-2.5, when starting sema, definitely start low and go slow with the dose increases. It helps minimize potential side effects. Also, focus on eating smaller, more frequent meals, and stay hydrated! Good luck!

This is just awesome to read! Way to go! Big celebratory hugs to you for not only feeling better about yourself but realizing you don't have to binge eat anymore. I'm excited to see your journey unfold :)

It diminishes everything. Lack of pleasure is a pretty common side effect with these meds (speaking from personal experience).

It's interesting how much emphasis is placed on the medication, but not on lifestyle changes! I saw a headline that said something about a 'groundbreaking discovery' that food may be making us fat, LOL. Maybe the relentless munchies are the problem and not just the weed?

I'm so glad to see this post! I live in a legal state, and I've always used cannabis heavily. It definitely contributed to my weight gain because everything tastes amazing when I'm high. I thought I'd have to stop completely while on tirz, but it turns out the tirz totally kills the munchies...

I get that on reta, a handful of whole grain crackers usually does the trick.

Just a note on a related issue, I've heard reports of reduced libido when taking Reta due to reduced dopamine production in the gut. Something to be aware of.

I dropped a bunch of water weight early on, and my weight went up and down. If I remember correctly, it took a couple weeks for the appetite effects to kick in for me, and even then it didn't completely kill my appetite. That was at 2mg a week. It got better when I went up to 4mg.

You're just at the beginning, Bee_Quest. Retatrutide needs time to accumulate in your system. The first month is really about preparing your body for the full effects. Keep reading the forum and maybe look into the clinical trials for retatrutide. Patience and consistency are key.

Congrats on smashing that milestone!

That's incredible! You look like you've knocked off a decade! And you just radiate happiness and confidence!

Sure! I started at the lowest dose and gradually increased every 4 weeks based on my doctor's recommendations and how I was feeling. I'm currently on a maintenance dose.

Tone_Diary Thank you! I mostly walk, about 30-45 minutes a day, sometimes a bit longer on weekends. Nothing too intense!

Hey everyone! I wanted to share my progress. I started this journey around May 20th, weighing about 303 lbs, and as of today, October 15th, I'm at 215 lbs. That's roughly 88 lbs shed in a little under 5 months! It's been tough, but honestly, it's so worth it. I've changed my diet, started a...

It's inspiring to see everyone's progress! As I get older, weight loss is more challenging, but medications like these are very helpful tools. Keep up the great work, everyone!

Fantastic!

Your complexion looks wonderful. You must be young!