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Three weeks at 2mg split is early - most notice appetite changes around week four to six.

Splitting the crimp ring off with the tip of a pocketknife takes 5 seconds - peel and it's open.

Generic sema at $3 manufacturing is plausible - the molecule is not complex at scale. Patent expiry is what holds the price; once it goes, the competitive compression is usually fast.

I love that you are starting, OwlLady! That is a GREAT idea. I wish I had started the probiotics before I felt sick lol

I wish I'd known that probiotics can really help with digestive issues (nausea, throwing up, upset stomach, heartburn, burps, reflux – all that!). A daily yogurt is good, but I added supplements when I realized how well probiotics work. Start now! Also, psyllium husk helps both with diarrhea...

Honestly, the best thing I did was find a good online community! I literally spent days absorbing everything I could from other people's experiences. Super helpful. Try searching for threads with keywords like "start," "first," or "newbie." There are tons of people asking the same questions, so...

I'm getting close to my first goal. Down about 25 pounds, but I can't wait to get to my ultimate goal. It's like I haven't weighed under 200 since high school!

Wow, that's amazing! You look incredible! So inspiring! 🎉

Just wanted to add something I forgot. Listen to your doctor! I know it sounds obvious, but some people get advice here and ignore their actual medical professional. That's a REALLY bad idea!

I'm starting to think it's about money. The carriers are all charging extra because of the conflict, maybe the shipping agents are having to re-quote and resend. Just guessing, though. It could also be that these vendors use the same freight forwarder, and *that* company is having issues.

Both of mine were stopped *before* leaving China, so it's looking like a China problem. Maybe it's the international situation causing delays?

In my case, I felt a bit sick to my stomach at first, maybe for 2-3 days. It got better as the weeks went by. Never threw up or had the runs. I stay away from fried and greasy foods. If you eat too much, you'll feel gross. Listen to your body. Stop when you're full, even if it's a small amount...

Has anyone else had orders returned lately? I've had a couple get sent back this week from different suppliers, one via expedited and the other via standard. Expedited said customs issues in China, waiting on the other. Is something up, or just bad luck?

I've only been on sema for a couple of weeks. I'm noticing I still want snacks, even when I'm not hungry. It's like my brain is bored or something. I've been trying to drink a lot of water, coffee, and protein shakes to feel full. Sometimes I'll just have a little bite of what I'm craving and...

Hey! Welcome to the semaglutide subreddit! Just a reminder, we aren't allowed to chat about semaglutide that isn't FDA-approved, and buying or selling meds is a no-go. Don't answer DMs from anyone trying to sell you stuff; we don't support that here. If you're new, maybe check out the FAQ...

Update: I stopped the ipamorelin a couple of days ago. Hoping to see some change in the next week or so. I'll keep you guys posted.

Thanks everyone, that's all good info.

I started the ipa Dec 23rd. 250mcg morning/night, 5 days on 2 off, plus tessamorelin.

I started the Ipa on December 23, so about 3 weeks now.

Yeah, Pops, that's what I initially thought about the increased hunger. I upped my Reta dose from 4-5 to 8, hoping that would counter it. But still, I didn't expect a month-long stall after it worked so well for the past two and a half months.