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I would've gone with tirz first if it was available, but reta was what I could get. Started at a lower dose, then bumped it harder because trial data showed bigger jumps worked better for weight loss. Honestly felt like time was the real factor - didn't want to waste months creeping up slow...

Interesting thread. Quick questions: think SIBO might cause my LPR? Best way to test? Bloating and constipation since I was a kid, better now but still IBS when traveling. Started kefir and chia, big improvement in bowel movements. Probiotics right dose? Mixing kimchi helps?

If you're a woman, are you dealing with perimenopause or menopause? I've read studies suggesting that low estrogen levels can reduce how well GLP-1 meds work in women. Some doctors are now prescribing HRT and seeing improvements. I'm in the same situation. I was on wegovy for about a year, at...

To push past a stall, try eating at your maintenance calorie level for two or three weeks. Your body might need to reduce cortisol levels to start losing again. Staying in a calorie deficit for too long can really stress your body. Also, reduce your exercise intensity during the maintenance...

Started sema in early Dec and by May 1 I'd lost 21.5 lbs. Hit a couple stalls and the scale bounced around, but slow and steady wins. Started at 278, down to 257, on 2.5mg (35 units). My doc's been conservative with bumps—every 4 weeks, not rushing. Is 21 lbs good? Yeah, I think so.

I had rotator cuff issues and tendon stuff. Used one combo stack last year, this time I put one thing right on the injury and another in the belly separately. Works. Pain's way down, range of motion is better, arm got stronger. Only done 7 doses though and not consistent.

Got a close friend, basically a sister, that I told about everything. She kept asking how I lost the weight and I didn't want to lie—she had a failed surgery and was really struggling. I explained the risks and side effects clearly. She was scared like she should be. But seeing my results, she...

My dad tried this med and couldn't make it past 2 weeks. Nausea and fatigue wrecked him. I'm on it for weight loss, mom takes it for blood sugar, so I see it from angles. Wondering if his experience is common. For people who almost quit early — what was worst? For those who did — what would've...

you need more protein and calories, it'll come back but takes time. hair and nails are last in line for protein when you're losing, so get more. have you noticed you're not cutting your nails as much?

Caught an episode of Science Quickly podcast talking about how the GLP-1 story's evolving. They traced it from diabetes treatment to blockbuster weight loss drug, then into all the complications with compounded versions. Landscape's way more complex now with all the new research angles opening up.

the big website everyone knows is doing fine despite mentioning their community. the fda's still a mystery - this time bac water was the focus, which matches the letters from other actions. who knows what they'll come after next, but they seem to stick to easy targets.

Maybe try adjusting your dosage a little? Or looking at what you're eating right before the cravings hit.

My numbers are close to yours. SW 123kg, GW 75-80kg. Started in July, I’m down 27kg. Back in the day (20-30 years ago), when I’d diet hard, I'd lose a good 4.5kg per month. But it didn't last. This time, I want 2-3kg per month, which is healthy. I worry about loose skin, so slower is better...

Hey all! I'm at the half-year mark. Not seeing the crazy fast results some share here (like 5kg a month), but it's been pretty consistent. Had a stall in February, upped my dose to .75mg, and things are moving again. Started at 123kg, then 121kg when I started the meds on Sept 26th. Now I'm at...

Usually they are supposed to be bioequivalent, but I guess we will have to wait and see!

Yep, I'm on a really low dose for keeping the weight off and it's working great.

You're so right! I used to love cooking and eating healthy, but now I just want frozen meals with extra veggies, or ice cream. At least I'm losing weight?

2000 calories is my target.

That's awesome! You'll feel so much better in clothes that fit properly. It's a great reward for your hard work!

Honestly, I don't track calories at all. I'm losing about a pound a week, so I don't see the point in tracking.