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The NEJM trial showed 15% average body weight loss at 2.4mg weekly over 68 weeks in non-diabetics - that's the data the FDA chronic weight management approval was built on.

Rescheduling changes dispensing rules, not the prescription requirement - a provider script is still required. Weight history plus comorbidities is what makes the PCP conversation land.

162 to 141 with 20 more to goal is the first chapter closing - the clothing changes tend to outpace the scale in what they actually show.

I'm only on my first week of using the medicine (.25mg) so things haven't changed drastically yet, but I'm hopeful after seeing everyone else's transformations! I'm using an app to save recipes and track my calories, and focusing on mindful eating.

I am a chocolate addict who does not want chocolate since starting tirz. I am surprised by this article. I have not craved chocolate in months. However, I will take a small handful of M&M's if they are around...because they're there.

I think Lindt might be right. At first I thought it was nonsense but Lindt makes premium chocolate. Many of us used to scarf down cheap snacks. Now that we don't have a voice screaming "eat everything," we can spend more on better quality.

Not me. I don't care about sweets now.

I agree with Meal_xo, slow progress is still progress and can be more sustainable! You got this! Don't give up. Plus, the reduced food noise is a huge win already!

Any progress is still progress, and 5 lbs when you're starting at 168 is awesome. Keep at it! For the first month, I didn't change my diet at all or even check the scale. I let my body get used to the medication and focused on small changes like less food noise, which led to less binging and...

I got some generic auto-injectors. They were pretty cheap with insurance. Can't be too safe, just do what you feel is right. Honestly, it's a good idea to have them around for any kind of reaction, not just for peptides - think meds, food, all kinds of stuff.

Sorry, I missed that earlier. I was just shy of a month on Tirz, taking 2.5mg twice a week. I took a couple more doses of Tirz to help bridge before my Reta levels were high enough to take over. No side effects except for feeling a little cold. Tomorrow will be four weeks since I started the...

Just to be clear, it takes around 4-5 weeks at a certain weekly dose to reach a steady state where the intake rate and elimination rate are balanced. That's why a weekly dose gives you a consistent average level of exposure.

So far, bridging from Tirz to Reta, getting my Reta levels up where they should be based on the trial data, has kept my hunger and food cravings totally in check. It's been about 10 days since I took any extra Tirz. My Tirz level is around 1.3mg right now, and I don't think I'll need any more...

And happier. ❤️

Wow, you look healthy and BEAUTIFUL!

The flushing starts in like 5-10 mins. I think I went up to 500-1000mcg of cjc and 350 of ipa. And yeah, I think it helped me keep muscle while I was cutting calories. I'm thinking of trying tesamorelin and ipamorelin soon. Supposedly it's the best combo.

I did an 8-week cycle of cjc 1295 (no dac) and ipa. It messed with my sleep instead of helping it, which apparently happens to a few people. Also, watch out for a flushed or tingly feeling right after the shot. It's normal and doesn't last long (like 15 mins). You might also get itchy spots or...

Wow, great results! Did you have many side effects?

Thanks for posting!

Congrats! Which company are you using? There are so many, I can't tell which is for real. Seeing your progress is inspiring! 🙌🏼