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The 6-week mental adjustment is common - the metabolic shift affects mood, energy, and focus in ways that feel disorienting even when progress is happening. GLP-1s can alter absorption of oral medications including psychiatric meds; worth flagging with your prescriber if relevant.

2 years for side effects to resolve is the long end - protein and water consistently is the main lever most people find it front-loaded in the first months.

Stopping a medication maintaining two positive outcomes simultaneously because it's 'working' is the logic that produces regain data.

Wow, wish that would happen to me!

You can reduce muscle loss while cutting. I went from 270 to 200 last year in 9 months. I ate a lot of protein, but only 1300-1400 calories a day. 150 grams of protein. I weighed everything. I lifted weights 3-4 days a week and did 30 minutes of zone 2 cardio 5 days a week. Every 3-4 weeks I'd...

I've been on for 4+ months, just now at 3.5mg, and only lost 20lbs. I lift 4 days a week and try for 100g protein daily, so I hope I'm not losing much muscle. I'm a 50s male and have another 15lbs to lose. A lot of people on Reddit are spreading misinformation that Reta spares muscle.

I heard some chatter about a generic version coming out sometime next year in Canada. Supposedly, it will be way cheaper.

That's awesome! I've seen the starting dosages around $200 if you pay out of pocket and use a discount. Congrats! Welcome! 🎉

I've struggled with insomnia for years and have seen a bunch of specialists. I've tried everything, even sleep therapy. My sleep had been pretty good for a few years, but then I started tirzepatide. It totally messed it up. I couldn't fall asleep and would often be up until 5 AM. Which is a...

I've also noticed my sleep is worse since I started Reta. My resting heart rate used to be in the 50s, but now it's in the mid-60s. And my sleep is much more restless. It's the biggest downside for me. I think I'll try cycling it, maybe 12 weeks on and 8 weeks off, and see how that goes. But...

A lot of public libraries have 3D printers now, and prints don't cost much. I know a lot of people don't go to libraries anymore, but they're still around.

Awesome!

I actually have one of those label-straightening gadgets, and it appeals to my slightly obsessive tendencies too. I used to use a different label maker, but the labels faded in the freezer and the software was a mess. Now I get these customized "name" labels from an online vendor; like $9 for a...

Been thinking about starting sema. Seeing these posts is inspiring! I'm around 200 and want to get down to 150-ish. Seeing this person's post about going from a size 12/14 to a size 3 is wild!

I'm always shocked when I catch a glimpse of myself in a glass door or something. Who's that skinny dude?

I get that feeling COMPLETELY! I used to dodge every camera. Big win seeing those NSVs!

Just for fun: About 106 vials of lyophilized peptide 3ml vials weighs 20oz. Your results may vary.

Saving money is a nice bonus, for sure. My grocery bill is way down since starting!

Wait... are you weighing the vials before reconstituting?

I am confused. The weight doesn't have anything to do with dosing. If you have 10mg total and your dose is 2.5mg, the vial has four doses. If you put 1ml of water in, you pull 25 units for one dose. How much did you inject?