Yes. Started on a smaller dose and worked up normally. Starting weight in the 230s, goal in the 180s, plateau weight landing somewhere in between. Took over a year total to get there. Began with calorie counting early on. Felt like a stall at times, then I'd see a steady couple pounds weekly again. Hardest part was watching super responders post losing 25 pounds in a month. Slow and steady really does win this race though. Good luck!