Mike_02
Active member
Hey everyone, I wanted to share my experience with Mounjaro. Please keep in mind that your journey might be way better than mine! It's kinda long, so bear with me.
I started Mounjaro around June 2025, weighing about 220lbs. Now I'm down to 172lbs, which is awesome! For the first couple of months, I was on 2.5mg, then I upped it to 5mg, and have been on that ever since. When on 2.5mg, I injected every week. On 5mg, I switched to every 11 days.
I didn't need to increase the dose because it wasn't working, but because of the bad side effects I had on the lower dose, like killer headaches, major anxiety, throwing up, etc.
Basically, I'd feel like crap for around 3 days after each injection:
Day 1: Horrible headache, super tired, mostly sleeping.
Day 2: Still stuck in bed most of the time, but I can at least get up a bit.
Day 3: Slowly getting back to normal.
After that, I felt mostly okay, except for some lingering anxiety and depression (more on that later).
I was prescribed Mounjaro for weight control but also because it's being researched as a possible treatment for endometriosis (which I have).
I can't take estrogen meds because they mess with my bipolar disorder. So, I also take a progestin-only birth control to deal with endo pain. Since starting Mounjaro and the birth control, my endo pain is gone! And weed seems fine too, lol.
Mental Health
I've got bipolar, BPD, ASD, ADHD, and anxiety, so if you can relate to any of that, here's what I went through on Mounjaro.
BPD: Surprisingly, my BPD symptoms have gotten better. I used to have emotional outbursts almost every week, but now it's more like once a month. So, that's been a plus. I still get angry sometimes, but it's usually because my blood sugar is low.
Bipolar: Before Mounjaro, my bipolar was well controlled. But the longer I'm on it, the more I've noticed a deep depression. No mania or hypomania, just lots of numbness, feeling disconnected, and not being interested in anything. It sucks and has made me think about stopping the medication. I spent like 4 years getting stable before this!
TW: I've had thoughts of suicide, but I wouldn't actually do it. Still, it makes me cry because I don't want that to happen. I'm lucky to have support.
Anxiety/OCD: This is where things got rough. I've always had anxiety and occasional DPDR, since Mounjaro, my intrusive thoughts are way worse.
I was recently diagnosed with OCD. I've always had OCD tendencies, but never enough to be more than just anxiety. I get paranoia (intrusive thoughts I know aren't real) and intrusive thoughts about my mental state and relationship. Doctors think it might be from dehydration, low blood sugar, and how the drug affects digestion and dopamine.
Physical Health
Migraines & Vision: Mounjaro has given me some brutal migraines. Sometimes I get visual problems like:
* Seeing things out of the corner of my eye (like thinking my cat is there when it's just a rug or nothing).
* Seeing objects "moving" when they're still.
Low Blood Sugar: Watch your blood sugar! One night I felt super dizzy and anxious. It felt like a panic attack, but I knew it wasn't. My blood sugar was super low. Low blood sugar has been a big issue for me on this medication.
Sleep: Sleep has been terrible. I'm tired all day, then wide awake at night. I've used sleeping pills sometimes, which I need because sleep is so important for my bipolar.
Dehydration: I have to drink way more water than before. Mounjaro can cause serious dehydration, and it can really mess with your body and mind.
Update:
I've been off Mounjaro for about a month! I'm at 172lbs, and I've been hitting the gym 5-6 times a week. The longer I'm off it, the better my mental health is. I'm slowly feeling like myself again, which is great. I still have off days, but they're less often. I'm thankful for the weight loss, but I wouldn't do it again! This whole experience has made me determined to make the gym work! As for the endometriosis pain, it's back, and I don't know what to do about it yet!
If you have any questions, feel free to ask! And remember that this was just my experience. Yours could be different, so don't get discouraged.
I started Mounjaro around June 2025, weighing about 220lbs. Now I'm down to 172lbs, which is awesome! For the first couple of months, I was on 2.5mg, then I upped it to 5mg, and have been on that ever since. When on 2.5mg, I injected every week. On 5mg, I switched to every 11 days.
I didn't need to increase the dose because it wasn't working, but because of the bad side effects I had on the lower dose, like killer headaches, major anxiety, throwing up, etc.
Basically, I'd feel like crap for around 3 days after each injection:
Day 1: Horrible headache, super tired, mostly sleeping.
Day 2: Still stuck in bed most of the time, but I can at least get up a bit.
Day 3: Slowly getting back to normal.
After that, I felt mostly okay, except for some lingering anxiety and depression (more on that later).
I was prescribed Mounjaro for weight control but also because it's being researched as a possible treatment for endometriosis (which I have).
I can't take estrogen meds because they mess with my bipolar disorder. So, I also take a progestin-only birth control to deal with endo pain. Since starting Mounjaro and the birth control, my endo pain is gone! And weed seems fine too, lol.
Mental Health
I've got bipolar, BPD, ASD, ADHD, and anxiety, so if you can relate to any of that, here's what I went through on Mounjaro.
BPD: Surprisingly, my BPD symptoms have gotten better. I used to have emotional outbursts almost every week, but now it's more like once a month. So, that's been a plus. I still get angry sometimes, but it's usually because my blood sugar is low.
Bipolar: Before Mounjaro, my bipolar was well controlled. But the longer I'm on it, the more I've noticed a deep depression. No mania or hypomania, just lots of numbness, feeling disconnected, and not being interested in anything. It sucks and has made me think about stopping the medication. I spent like 4 years getting stable before this!
TW: I've had thoughts of suicide, but I wouldn't actually do it. Still, it makes me cry because I don't want that to happen. I'm lucky to have support.
Anxiety/OCD: This is where things got rough. I've always had anxiety and occasional DPDR, since Mounjaro, my intrusive thoughts are way worse.
I was recently diagnosed with OCD. I've always had OCD tendencies, but never enough to be more than just anxiety. I get paranoia (intrusive thoughts I know aren't real) and intrusive thoughts about my mental state and relationship. Doctors think it might be from dehydration, low blood sugar, and how the drug affects digestion and dopamine.
Physical Health
Migraines & Vision: Mounjaro has given me some brutal migraines. Sometimes I get visual problems like:
* Seeing things out of the corner of my eye (like thinking my cat is there when it's just a rug or nothing).
* Seeing objects "moving" when they're still.
Low Blood Sugar: Watch your blood sugar! One night I felt super dizzy and anxious. It felt like a panic attack, but I knew it wasn't. My blood sugar was super low. Low blood sugar has been a big issue for me on this medication.
Sleep: Sleep has been terrible. I'm tired all day, then wide awake at night. I've used sleeping pills sometimes, which I need because sleep is so important for my bipolar.
Dehydration: I have to drink way more water than before. Mounjaro can cause serious dehydration, and it can really mess with your body and mind.
Update:
I've been off Mounjaro for about a month! I'm at 172lbs, and I've been hitting the gym 5-6 times a week. The longer I'm off it, the better my mental health is. I'm slowly feeling like myself again, which is great. I still have off days, but they're less often. I'm thankful for the weight loss, but I wouldn't do it again! This whole experience has made me determined to make the gym work! As for the endometriosis pain, it's back, and I don't know what to do about it yet!
If you have any questions, feel free to ask! And remember that this was just my experience. Yours could be different, so don't get discouraged.
