Noticed with this medication that once a few months passed and the body genuinely settled in, mood shifted toward something far steadier too, way less depression showing up. Science is still catching up on how complex these drugs actually are, but the payoff at a real therapeutic dose is genuinely impressive. Lowering inflammation seems to improve things well beyond just the weight piece, and researchers suggest that's not purely a downstream effect of losing weight either. Comfort food still happens occasionally, but like others have mentioned, much smaller portions end up being genuinely satisfying.