Mounjaro making me crazy?

Hong Kong Yanpep International
Hawkxx said:
I've been feeling down because food just isn't enjoyable anymore. Not rage, but definitely unexpected emotions. Been on it for about 2 months.
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Yeah, it's weird when food loses its appeal. Like, what's the point of anything? LOL. Seriously though, I hope you find something that brings you joy again.
 
Protein shakes could help. And don't dose again until you can actually eat something. The med isn't supposed to stop you from eating, just make portions smaller.
 
It's interesting how people react to weight loss comments. Some love it, some hate it. Maybe just try to focus on how YOU feel about your progress, Shannon_1995.
 
Sam_93 said:
It's interesting how people react to weight loss comments. Some love it, some hate it. Maybe just try to focus on how YOU feel about your progress, Shannon_1995.
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That's a good point. I'm trying to focus on the positive changes in my health, not just the number on the scale or what other people think.
 
14.8 to 6.2 A1c on Mounjaro is a dramatic and rapid improvement that changes the dosing math for any outside insulin you're running. The blood sugar dropping to 9 mg/dL alongside that kind of A1c change is a medication adjustment situation that needs the prescriber involved. What does your endocrinologist say about the combination?
 
I'm autistic and ADHD, and I've noticed way more meltdowns plus trouble regulating emotions since starting mounjaro for my diabetes. My best guess is it's tied to my ADHD medication not working the way it used to since starting and staying on the 2.5mg dose. Been genuinely frustrating. Also doing a split dose twice weekly to manage blood sugar better. Hoping things smooth out for you too as time goes on!
 
This medication can indirectly touch serotonin levels, so it's possible that's contributing to her mood shifts. Worth bringing up with her doctor directly.
 
Man, been on this medication seven or eight months now. These past couple months I've started randomly tearing up at work for no clear reason, ha.
 
Yeah, this matches what plenty of others have said. It's not purely appetite related, from what I understand this class of medication acts on brain receptors directly, not just in the gut. Newer research points to those receptors showing up in spots connected to mood and stress response, which probably explains why an emotional shift is showing up for you too, beyond appetite. That steadiness even on a rough day is genuinely something, and nobody prepares you for it beforehand, everybody expects nausea and then discovers the real change is that mental chatter around food finally going quiet. Your body stops pushing back against the deficit like before, since the drive that once nagged you toward eating more has settled down, so cutting back just feels normal instead of like punishment.
 
Wanted to offer a little hope here, dealt with this exact thing after starting mounjaro myself, mine finally settled down after roughly 8 months. Hoping yours doesn't stretch that long since it's genuinely rough. Meat was my biggest trigger so I mostly cut it out and stuck to smaller portions, then one day it just cleared up on its own! Wishing you the best.
 
How much Lantus are you running currently? Insulin, particularly at higher amounts, can drive weight gain and make losing it tougher. Surprised your care team hasn't brought this up, it's fairly well documented.

What's your blood glucose looking like, and have you had recent labs done? There might be room to cut back on insulin, maybe even drop it entirely, if Mounjaro's carrying enough of the load and you're able to stick with it (what you're going through sounds genuinely frightening).

Sounds like a really tough stretch right now. Thinking of you and hoping you get some real answers soon.
 
Honestly never dealt with food noise, not even once. My ADHD presents as the type that just forgets to eat. That said, my hypoglycemia's been getting worse, and after around 13 years it's progressed into insulin resistance. At this stage, skipping regular meals with enough carbs leaves me shaky, cold, then confused, lightheaded, and pushing through without eating can make me pass out.

Summer's always brutal for this, on top of Hashimoto's, which means I basically can't handle heat, and since my ADHD keeps me from getting a license, I rely on walking or transit. So getting to work leaves me sweltering and my glucose tanks shortly after I've had breakfast.

Since starting the third compound, I can actually go without eating for once. No more crashes even with barely anything in my stomach. Like, a handful of bites at lunch and I'm fine clear until 9pm without hunger or a sugar drop. Feels like I'm finally free from being ruled by food and constantly bracing to faint. Can even brush off hunger without paying for it later, and that gnawing sensation that always meant a crash was coming just doesn't show up anymore. Can't get a continuous monitor where I live, so over the years I learned to read my own body's signals instead. Problem is, this medication works so
 
Been through that. Peaked at an A1C of 12.6. Started on metformin, later added a different diabetes medication. Dropped to 6.0 after six months. Didn't actually begin the dual-action medication until my numbers fell into prediabetic range.
 
Used to rely on low carb and keto to manage my weight. But since switching to mounjaro, I've noticed I actually need carbs now or I start feeling really unwell. Keto tends to suit people whose bodies struggle to produce insulin properly. This drug class improves insulin sensitivity, which means finally being able to eat a more balanced diet.
 
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