Yeah, some people swear by it, others not so much. My husband says he gets a little energy from NAD+, but it's gone pretty quickly until his next shot, so he doesn't "feel" it that strongly either. He's glad he doesn't feel jittery. He's trying to figure out his ideal routine; right now, he's doing 50mg twice a week. He wants to try going up to 100mg to see if he notices a bigger benefit. Then he'll stick with whatever works best. We'll see if he thinks it's worth continuing.