Oops! Maybe Went Too Hard on Reta...

Hong Kong Yanpep International
A couple of weeks at 5mg and no effect yet is consistent with quality issues or a slow early response. The 5mg mark is where most people start noticing something, so a few more weeks before drawing conclusions makes sense. What did the jump from lower doses feel like?
 
the four-day rough window at 0.5 then clearing to minor is the standard pattern - the first few days at each new dose level are the worst of what that dose will produce, and it usually stabilizes significantly by day 4 or 5. the OTC support during that window is the right call for getting through without backing off a dose that would otherwise work
 
Actually moved up to 4mg this past Sunday. Might just be in my head, but it felt like a noticeably strong shift. Started at 1mg, bumping 1mg every three weeks. Barely noticed anything on the earlier increases, but 4mg hit differently. First off, zero cravings whatsoever. It's Friday night and I've eaten considerably less all week since Sunday. Normally around Thursday I'd start feeling mild pulls toward food, nothing this time. Also was averaging roughly 1kg weekly on the earlier amounts, this week I dropped 1.7kg. Could be coincidence or placebo, but there's genuinely something different about the 4mg level. And for what it's worth, I haven't dealt with any major side effects since starting Reta, and the 4mg jump hasn't changed that. Only thing worth mentioning is ongoing constipation, though manageable, nothing overwhelming. Staying hydrated and eating enough fiber daily keeps it under control...
 
Did you deal with much in the way of side effects jumping straight into Reta at 6mg? Sounds like weight loss wasn't really happening for you though, which is kind of unusual.
 
Twelve days on this forum and suddenly you're the authority compared to folks who've been running Reta way longer and done fine with these bigger amounts. Trust me, 9mg's nothing to worry about. My wife and I both took that same amount this morning without a single issue. Curious, what's your actual timeline on Reta so far, and how old are you?
 
Started at 250mcg, felt zero effect. .5mg brought on some queasiness for a stretch that faded out. Planning to move to 750mcg next week. Also running reta at 6mg currently.
 
Everyone's got such wildly different takes on reta, hard to know what's actually right.

Looking back, probably should've listened to the go-slow, give-it-a-month crowd. Started at a small amount and felt it a bit the next morning. Moved up after about a week and felt hunger hit harder than before a few days after dosing. Settled into a routine every five days and things went smoothly.

But after reading that this compound only really kicks in at a higher amount, felt compelled to push the dose up even though the lower one was already doing its job. First week at the higher amount felt low, almost like a mood crash, no motivation for anything. Getting to the gym took real effort, forgot to eat entirely one day, genuinely rough stretch. Two weeks in at that amount now and it actually feels good. Barely any food cravings, but can still eat what's needed. Just have to set reminders to avoid accidentally undereating for the day.

The two biggest tradeoffs at the moment, feeling genuinely weak at the gym since intake's still too low to perform well, which is probably slowing progress and maybe costing some muscle. Other downside is bathroom unpredictability, used to run like clockwork but now there's no telling.
 
Reta for me began mid June at .5 mg, now I am on 1.5, going to 2 mg next week. Going very well. Lost 20 lbs, and my food noise stays quiet most days. Only downside was lots of sulfur burps early on when I forced protein in. They faded, I think thanks to probiotics, a digestive enzyme, electrolytes and eating less fat. I enjoy how it feels, even the mild anhedonia. Honestly it helped me finally get out of an abusive relationship and I have never felt better.
 
I frankly did 0.25 twice weekly, working up to 1 mg a week of reta. A couple frankly of weeks ago I went to 1.5 but my appetite dropped quite a bit, so I dropped back to ONE and that works for me.
 
I'm a super responder. Three weeks at 2.5mg at the start made me miserable. Vomiting, nausea, fatigue, and no hunger or taste for food. Any side effect labeled nausea, my body signs up for. I should have asked my doctor about a lower starting dose. Round two began below 1mg and climbed back to 2mg. 30lbs gone since May, with 15-20lbs left to my target.
 
Know you only want replies from 3mg folks, but chiming in. I hit a similar wall. Started at .5mg reta and it was a game changer. Six weeks in it quit on me, the food noise returned, so I stepped up. 1mg still did nothing. Held two weeks, moved to 1.5mg, nothing again. Latest tweak: shots at 1.75 spaced 5 days apart, not weekly, and it looks a lot better.
 
Another update: lost another pound. Guessing 1mg just wasn't enough for me? Can the body even plateau that fast? I dropped maybe 5 pounds in the month before and held steady before starting Reta. I'm 5'8 195 now, started at 200. How's everyone's sleep? Mine's much worse but I'm hanging in.
 
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