Reta kinda working? Still unsure...

Hong Kong Yanpep International
Too soon to call yet. Takes some folks longer to kick in. I didn't notice much at first either when I used a telehealth provider.
 
Delayed response is common enough to warrant a few more weeks before adjusting anything - early signal can still build into real suppression.
 
Nausea at day six means it's active - full appetite suppression usually follows the GI adjustment by a week or two.
 
Day 6 at 0.5mg is very early - the suppression effect for reta typically starts showing more clearly around week 2-3 at that dose. The nausea you felt this morning is actually a signal it's working. Craving pizza at day 6 doesn't mean it's not working - the full appetite change takes longer to establish. Splitting doses early like you did can extend the side effect window, so it's worth giving a consistent dose schedule a few weeks before adjusting.
 
4th dose at 1.5mg is still the very beginning. A day or two stall at that point is just the body adjusting - the full picture usually takes a few weeks at a consistent dose to be readable. Don't change anything yet.
 
constipation causing nausea is the feedback loop that catches a lot of people on GLP-1 off guard - when gastric motility is already slowed, any additional backup amplifies the nausea rather than adding a separate symptom. the unwell feeling that comes with it is the whole-body version of a system that needs help moving things along, and resolving the backup usually clears both symptoms together
 
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