Reta plateau at week 10 - dose up?

[Macro_Ready]

Ten weeks with 30 lbs down and a two-week stall is not a plateau - the curve resumes. Data pattern at this stage is normal.

 

[sourdough-whittler43]

A brutal first week like that is exactly why people need to stick with it - once you get past the initial phase the body adapts and it becomes sustainable. 20 lbs from 1mg with minimal muscle loss is a good early number. What dose are you on now and what's the trajectory been?

 

[Alex_33]

The rule-of-thumb is a rough guide - 'stay if losing' makes sense, but 'stay anyway if side effects' even without loss deserves a closer look. If side effects are at the level they're affecting quality of life and the scale isn't moving, holding through that combination longer doesn't serve either goal.

 

[Chris02]

Starting April 6th as well. The jump from 1mg to 2mg is where most people feel it - .5mg steps are definitely easier on the system. 30 lbs and a plateau at week 10 is still a strong result. How's appetite at current dose?

 

[slim_sketcher]

the risk-calibration logic is sound. the downside of staying at 2.5 is just that you might need two doses, which is annoying but manageable. the downside of going to 5 before you're ready is actual bad side effects that can set the whole thing back. at 30 lbs in ten weeks there's no urgency here, the current dose is working.

 

[freshstart-weekly54]

Honestly sounds like a bad move. It's clearly working right where you're at, so no reason to bump the dose yet. You go up once you actually stall, and the next step for you would land at 7.5.

 

[Terry55]

Bump the dose up, just not right before a vacation. An all-inclusive trip is basically guaranteed to add some weight back regardless.

 

[thyme_simmerer]

Honestly I don't see an actual plateau on that chart. Also, nothing meaningful changes in just 7 days regardless. If it really was a plateau, bumping the dose might help, but even then you wouldn't notice anything in a week.

 

[plateau_again]

Thanks for clearing that up. Is bumping the dose an option if you wanted to? Has it actually worked well for you so far?

 

[lean_tofu]

Checking back in a week later... the stall broke once I bumped Reta up to 2mg and I finally cracked into the 200s! 298.8 pounds!

 

[noodle-reset41]

Was that running reta, and what was the starting and later amount? Also stuck in a four-week plateau here, started at 2mg losing close to a kilo weekly, bumped to 3mg a month back right as the plateau hit, and moved up to 4mg just this week.

 

[quinoa-wk689]

ten weeks today. basically Started at 2mg and I'm at 4mg now, going up .5mg every 2 weeks. I'll probably sit at this plateau a while until I feel like climbing again. I'm taking a month off for travel in Nov, I'll likely go down after that. Hunger hasn't been an issue because I began, and I've been great about hitting 150g-200g protein daily.

 

[redfang]

Week two at 10mg for me. Possibly another week or two at 10mg to check whether the August plateau gives way, but 12mg is tempting, since it fits the phase 2 trial ladder of 2mg, 4mg, 8mg then 12mg better. This past month was rough, more so after 6mg and early 8mg went so well. Deficit plus six workout days a week has been my routine.

 

[Dippercatapult]

2.5mg worked for roughly 5 of my first 8 weeks. One week I regained everything from the week before and two were flat, so I asked and went to 5mg in week 9. Since then I'm dropping 1.27kg (2.8lbs) weekly on 5mg, 8 weeks on each dose so far. I asked for more since appetite suppression was fading around day 4 or 5 of the week. Eight weeks into 5mg it now fades on the evening of day 6, which I just push through. If I keep losing I'll stay on 5mg, and I have basically no side effects there. I only swapped because effective loss stopped, though I still averaged 1.4lbs (0.63kg) weekly on 2.5mg. Over 16 weeks that adds to 28.5lbs (12.92kg). 76.5 lbs, or 34.7 kg, remain until my target of 180 lbs (about 81.6kg). I doubt I'll reach it, yet a goal was needed.

 

[salty_intransit2462]

Chris02 Like the others say, a slow pace wins. Your weekly amounts sit at the low end. 2mg usually counts as a starter dose, and beginning low like you did was the right move so your body could adjust. Personally, 2mg seems a high start to me, so I'd go lower for the first weeks regardless. Reta's half-life runs 6-7 days, so a 1mg Monday dose leaves about 0.5mg on board by Sunday. Add another 1mg the following Monday and 1.5mg is in your system, so levels rise fast. I'm at 2.5mg weekly and losing a steady 1.5lb a week, which suits me. I don't plan to climb far above that. Have you noticed the reduced appetite?