Reta stopped working?!

Sarah30

Sarah30

Member
Ok, so I'm looking for some advice. I started Reta at 2mg a week, didn't feel a thing really. After 3 weeks, I bumped it to 4mg, split into two doses. That's when things started happening; appetite was way down and I dropped about 10 pounds in a month. But at week 3.5, bam, the suppression vanished. I stuck it out for the rest of the month. Now, I'm on 6mg, split into two doses, hoping for a repeat, but nada. Still hungry, the food thoughts are constant. Is this normal? What am I doing wrong? Any help would be great.
 
Sema gives the most appetite suppression, in my experience. It sucks recommending something new, but sema is usually affordable. Instead of increasing the Reta (and using it up), try a small dose of sema.
 
I'm having the same thing happen at 5mg. It's been a few weeks since I upped the dose, and I still get appetite suppression and I'm still losing weight, but I notice I’m experiencing more food noise; it’s not as good as at the beginning. Should I increase my dose?
 
Okay, I’m going to try one dose a week and if that doesn’t work....Cag it is! Does anyone have any idea why there is so much confusion with the recon solution? Vinegar??? What is going on?
 
I can relate @Sema_Sister, I've been on sema and then trizepatide since last year. I started at 185 and went down to 169. But now I'm back up to 175, even 178! I'm at the gym, running, and eating healthy. It's frustrating to gain weight when it feels like I've barely lost any in over a year!
 
Jules_1986 said:
But now I'm back up to 175, even 178!
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What dosage are you currently using? Also consider getting bloodwork done to rule out any other underlying causes. A hormone panel could be insightful too.
 
I hear you, @Sarah30, it can be frustrating when things stall! I started my shots in June. Food noise stopped and the weight came off fast. But since December, the scale has barely moved. I'm at 1mg now. I'm grateful, but it's not as strong as it was before.
 
I had supply issues mid-cycle and switched pharmacies a couple times too. New place is stable for now, but I keep wondering what will happen next refill. Seems like it keeps helping even after I stop for a bit, and I've really changed how I eat.
 
Ipamorelin cranked my appetite hard. Thought Retatrutud quit working. But since starting it I'm doing strength work and muscle jumped. Not sure if Ipamorelin and CJC pushed it further.
 
The anhedonia response on Reta is one of the more consistent side effect patterns - it tends to accumulate rather than appearing immediately, which is why the 4-week washout usually resolves it. The restart strategy with lower-dose increments and a slower titration rate is the main way to avoid hitting the same threshold on the second run.
 
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