Reta/Tirz Cycles - am I crazy?

[rustic-fig70]

Been running triz since November, planning to start stacking once my first Reta shipment lands next week. Currently at 6mg split across two weekly doses of triz, planning to kick off Reta at .5mg and climb from there if it seems necessary.

 

[fig_month3]

Never actually tried this personally, but plenty of threads describe alternating a set amount of one compound for the equivalent amount of the other on a weekly or biweekly rotation.

 

[figuringoutsleep85]

You'll likely need to hit the same dose or go higher this next round. There's research showing cycling on and off builds up resistance to the treatment, at least in animal studies.

 

[cottage_titrating]

100%. Started reta back in June at 2mg weekly. Had been maxed out on tirz for a full year prior. Cut that dose in half rather than dropping it entirely since I still wanted the mental food chatter kept quiet. Mostly worked out that way. Tried a week running the complete 15mg tirz alongside 4mg reta, wasn't terrible but wasn't great either. Went back down to 7.5mg tirz since reta's clearly carrying its weight. Meanwhile I've been climbing on reta gradually, bit by bit.

Currently running 3mg every other day. Works out to roughly 9mg weekly overall. Feels like the whole half-life conversation might not be fully settled science yet. And like everything else, bodies vary wildly. Every-other-day dosing seems to keep reta's benefit genuinely active in my system in a way that twice weekly never quite matched. At least for how my particular biology handles it.

 

[bagel_freshstart]

Currently running tirz at 10mg, split across doses. Planning to fold reta into the mix in about two or three weeks, starting low and just seeing how my body reacts. Doubt tirz and reta translate 1:1 dose-wise, so I'll hunt for whatever reta amount triggers the effects and use that as my starting point.