Sema or Tirz: Which to try first?

[Dipperbrownie]

Sema's just worked better for my body. Never felt right on Tirz, and the scale didn't move for me on it either.

 

[sage-ginger97]

Worth trying the other major medication in this class. Some people who struggle with one option find better results switching to the alternative.

 

[crispy-chopper426]

Tirz isn't automatically the better call for everyone. Sure, it's a GLP-1 and GIP combo, but it leans more heavily GIP. If your body actually responds better to the GLP-1 side specifically, it'd make sense sema ends up working better for you.