Sema stopped working... switch to Tirz?

[rustyplugging]

60 on sema and then another 100 on tirz is the two-mechanism approach playing out over time. The switch makes the most sense when sema has genuinely plateaued rather than just slowed down. Individual response drives a lot of this - the overlap in mechanism explains why some people get a big reset on tirz and others don't.

 

[hazy_doodler]

Tirz never worked for me either. Switched over thinking it'd do better, but ended up yo-yoing the same 15lbs for half a year. Went back to sema roughly six weeks ago and already down 10lbs. Know some of that's water weight, but honestly thrilled regardless.