Still hungry on week 2?

Not sure about estradiol management but TRT alongside GLP-1 does come up a lot in here. A lot of people run both. There might be a thread specifically about it if you search - more people with experience would be there than in the week 2 hunger thread.
 
Still dealing with constant hunger and food thoughts here too. For me, the shot helps with restraint and sticking to smaller meals, but the appetite doesn't just vanish. I'm in the gym 60-70 mins most days plus cardio, so that probably keeps hunger higher than it might be otherwise.
 
Hunger on week 2 after a dose bump is the adaptation phase - the appetite suppression often runs behind the new dose by 5-7 days before it catches up.
 
GLP-1 gastric emptying delay means the 'full signal' arrives late during week two - the stomach holds more volume with slower mechanical feedback. Eating through that delay is what causes extended discomfort.
 
Second-week hunger at the starting dose is normal - the first week's effect is partly initial response, and real suppression builds gradually as the dose increases.
 
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