Weight Coming Back After GLP-1s?

Hong Kong Yanpep International
About a pound per week was regained in the study I read.

I set a target weight for myself and only use a smaller 'maintenance' dose when I go over it. I'm not sure if it's a good idea, but even when I took a tiny dose every two weeks, I kept losing. I want to stay where I am now.
 
I'm thinking about staying on them for life, just at maintenance doses. Because my brain isn't so obsessed with EVERYTHING (food, alcohol, shopping) anymore, and my head is much calmer now.
 
We can definitely revert to our previous behaviors, but I hadn't considered it from Grogu's and others' viewpoints. I suppose it depends on your starting point!

I've found that GLP-1s have helped me develop the habit of eating two large meals each day. I'm essentially doing intermittent fasting without any conscious effort. They say it takes more than 20 days of consistency to develop a habit. I suspect that's accurate, but I was also in a relatively "privileged position". I'm only about 110 pounds over my usual weight, and I'm also tall, which seems to make it easier to achieve a caloric deficit (I'm not sure if that makes sense, but it's my perception).
 
Thanks for sharing that video. When she began with "Do you need to stay on GLPs for life? The short answer is...it depends." I was hooked.

It's great to witness someone acknowledge that we all have a different beginning and might have varying requirements for health maintenance. Not many of the YouTube peptide personalities appear to do that.
 
I am in agreement with
Claudia_Way said:
People don't like to think about it, but mental effort is limited.
Because of this I think I might actually go ahead and stay on them forever. I simply don't have the willpower to manage otherwise.
 
You know, some people have to stop these meds not because they want to, but because they have to. I saw a post on Reddit where someone has been on Mounjaro for over a year and lost a good bit of weight, but then started having lots of GI problems. Hopefully some of the new drugs coming out will be easier on the stomach.
 
That's interesting. I wonder about the long term ramifications of peptides like Ipamorelin/CJC-1295 too. I saw a post from someone who was taking them for the better part of a year and couldn't tell if they were doing anything at all. It seems like some folks respond better than others. I think I'll stick with the GLP-1s for the time being.
 
Fast if the scale stalls after a week. Do an LMNT at 18 hours then 24-48 hour fast. Every time I do that, I lose and it stays off. Keep me on track for weekly loss. 24-48 hours burns serious fat.
 
Whatever direction you decide on, check a half-life calculator for your plan. Cutting back creates the same unexpected pharmacology as ramping up. For instance, if you wanted to go from 3mg weekly to 1.5mg weekly, you'd skip the next shot then restart 1.5mg two weeks later. Counter-intuitive but gets you steady in one week instead of dragging it out a month.
 
The GLP-1 only versus GLP-1/GIP difference is real and does change how the body responds. Some people who plateau on one find the other picks back up. The regain pattern after stopping either of them is the harder conversation - most people who stop do see some weight come back.
 
the temporary-medication framing for GLP-1 is the one that leads to the most predictable disappointment - if the underlying mechanism was always a matter of medication-supported weight regulation rather than a one-time correction, stopping it and expecting to hold the result is not supported by the biology. the sub's standard framing on this is accurate even if it is not what people want to hear when they are considering starting
 
The window of opportunity framing for maximum weight loss before stopping is underexplored in most of these discussions. The combination of multiple mechanisms during active loss versus the single-agent maintenance question is where the long-term trajectory gets complicated. The honest answer is that most people who stop regain, and the unknown variable is whether aggressive combination during active loss changes that.
 
Varies a lot from person to person.

Some people barely gain anything after stopping these meds, others end up putting it all back. Plenty fall somewhere in between too.

Worth asking your doctor to run bloodwork and the usual checks to see where things stand for you specifically.

But if you keep putting in real effort after stopping and don't slide back into old unhealthy patterns, a dramatic regain probably isn't likely, though do expect some gain since that's pretty common regardless.

Can't recall the exact name, but there's a community out there where people track their weight over time after coming off GLP meds, worth searching for if you want to see how it's played out for others.
 
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