Restarting GLP-1 after surgery?

Hong Kong Yanpep International
10mg to 7.5mg to 5mg over 22 months while maintaining the diabetes management piece is the step-down maintenance story that shows the medication can work at lower doses than the peak loss dose. The insulin adjustment at the lower dose is worth tracking - the A1C improvement to 5.1 is already at goal.
 
Recently underwent major abdominal surgery. Shifted the dosing schedule to leave a six day gap before the procedure. Resumed with the next dose three days post-surgery. Surgeon had no concerns with that timeline.
 
Might be worth pausing for a couple weeks to give your gut a break, then restarting back at 0.25mg. Definitely bring this up with whoever's prescribing too, get their take before moving forward.
 
Yes, definitely talk to your doctor about it. Been on a GLP1 since 2023 myself and I'm about to go three weeks without it for an upcoming surgery. Planning to restart at the lowest dose once I'm cleared.
 
Started at a small amount eight months back for type 2 diabetes. Glucose control's improved a lot and a substantial amount of weight has come off too. Was thinking about asking the doctor about moving up, but from reading around here, staying at a lower amount until it stops working seems like the better approach. Side effects have stayed limited to occasional nausea, curious what bumping up might actually change.
 
Good luck w/ the surgery. Whatever the research says, you'll have to follow the wishes of your surgeon or anaesthetist, or they may refuse to proceed. A few weeks of extra hunger and a few extra lbs should be easy to fix once you restart the GLP meds. Searching the medical literature, there are hundreds of studies on surgical outcomes with and without GLP drugs. Nothing definitive, and some show worse outcomes, but overall GLP drugs improve post-surgery results, particularly orthopedic ones.
 
I had to pause a week before & a week after surgery, since general anesthesia constipates you for several days and things need to move again first. Hunger returned and I put on 4lbs. The question was restart at the old dose or lower. I went lower & gained another 2lbs, then I went above my old dose across 3 weeks. That worked, the weight came right off mostly because the higher dose crushed my appetite. Now I'm at my old dose and back to my pre-op weight, everything stable. In the end it wasn't a big deal, just a process. I'd like to hear from anyone who went straight back to their old dose after 2-3 weeks off.
 
Ive had a run of surgeries lately, so I have a few data points on how surgeons view restarting glp1s. All said 2-3 weeks, mostly to be past the highest risk of unplanned post-surgery anesthesia trouble. Asking the surgeon directly is the safest route. Tell them she intends to restart a glp1 and ask what timing suits. A cosmetic surgery practice answers that question daily.
 
Every clinical study shows regain follows stopping. And if you've been off over two weeks, most providers restart you at 2.5mg to limit side effects, because your body's receptors have to readjust to the drug slowly.
 
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