Vision probs on GLP-1s?

[Tale_Teller]

I saw an article suggesting that maybe 0.5% of users could have some optic nerve problems after maybe 2 decades on semaglutide. The article says the nerve damage is probably permanent but doesn't necessarily affect both eyes. All the study focused on was sema. https://www.gbnews.com/health/ozempic-linked-rare-irreversible-vision-loss-large-scale-trial

 

[ThinTale]

Who's been taking sema for 20 years already?

 

[Tale_Teller]

They're estimating what that rate would be by looking at the data they have so far.

 

[ThinTale]

Aren't diabetics already more likely to have vision issues anyway? Ozempic, which is sema, was originally made for them.

 

[Macro_Manager]

It's an extrapolation.

 

[New_Lean]

My eyesight in one eye has been worse for about half a year now... could be totally unrelated though.

 

[Tale_Teller]

New_Lean You should definitely get it checked out. There are other GLP-1 options if necessary.

 

[Checkup]

My eyesight is terrible in both eyes. Started when I was a teen. Nearsightedness, astigmatism, the whole shebang.

 

[RetaReadyy]

I'd risk it to lose weight.

 

[Fox_Diary70]

I saw vision problems are a potential side effect of Tirzapatide as well. It does worry me.

 

[ThinTale]

That's not how proper research is conducted.

 

[Macro_Manager]

I agree with ThinTale. I'm just explaining what they're doing in the article.

 

[CoolFixed]

It makes for a catchy headline, though!

 

[Tale_Teller]

Am I the only one who is waiting for more bad news about these drugs? Honestly, if there's a 0.5% chance of vision loss, that's a much better trade-off than other health problems that being overweight can cause. I'll take it!

 

[ThinTale]

Pick your battles, I guess. A small chance of vision issues when I'm older is probably preferable to a heart attack at the same age.

 

[Macro_Manager]

I'm not sure about this study. How can they assume that 1 in 200 people will have vision loss after 20 years of sema use? I assume that in 2 decades of diabetes, at least 1 person will have vision loss from *not* using sema. I'm not a scientist, though.

 

[Tale_Teller]

It's a standard method for writing research papers. Whether or not you agree with the method is another story.

 

[Fox_Diary70]

Remember when they'd tell young men that certain habits would make them go blind? Never happened.

 

[New_Lean]

It's been addressed. I'll find the video.

 

[RetaReadyy]

This YouTube video is super boring. If you're a statistician or a doctor running similar studies, maybe it's helpful. They barely talk about the study.